Genetic Basis for Adverse Events after Smallpox Vaccination
نویسندگان
چکیده
منابع مشابه
Genetic predisposition for adverse events after vaccination.
The host response to infection or immunization varies within a population. Historically, we have ascribed variation of response among individuals inoculated with identical vaccines to stochastic processes that could not have been predicted. Now that the human genome has been defined and extensive variation in the ge-nome has been noted in both coding and regulatory regions, we can consider the ...
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lion recipients were reported; the next day, after noting that only 200,000 additional persons had received vaccine, the total swelled to 4.4 million (9). These data reflect the difficulties intrinsic to managing such a massive program. The discrepancy may simply be a case of not adding columns of numbers in a systematic way; however, the fuzzy numbers do have a certain appeal to the modern, mo...
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CONTEXT Recent anthrax attacks in the United States have raised concern about the nation's vulnerability to a smallpox attack. Many strategies have been suggested to minimize the impact of such an attack, ranging from quarantine and vaccination of case contacts to resumption of routine vaccination. Before the latter strategy is adopted, an understanding of the likely consequences of mass vaccin...
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OBJECTIVE To study the occurrence of adverse events after administration of a capsular polysaccharide vaccine against 23 pneumococcal serotypes in individuals for whom such vaccination is indicated. METHODS This was a prospective study, conducted in a general hospital in the city of Sumaré, in which 152 individuals were evaluated after intramuscular vaccination with 0.5 mL of the Pneumo 23 va...
متن کاملSmallpox Vaccination
This article was presented by the author at the Vaccination Seminar of May 26, 1972, National University Medical School.
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2008
ISSN: 0022-1899,1537-6613
DOI: 10.1086/588670